There are several treatment options available for acromegaly. The type of treatment you receive depends on the size and location of the pituitary gland tumour, or adenoma, severity of symptoms, and your current medical health.

Goal of treatment

The goals of treatment for acromegaly are to:

  • Lower your growth hormone (GH) and IGF-1 (insulin-like growth factor-1) hormone levels to what they were before the adenoma started releasing GH
  • Shrink the pituitary tumour
  • Decrease the symptoms
  • Prevent complications of acromegaly

Treatment options

The three main approaches to treatment for acromegaly are:

  • Surgical removal of all or part of the pituitary adenoma
  • Medical therapy using somatostatin analogues and/or GH receptor antagonists and/or dopamine agonists to:
    • Lower the production of GH in the body
    • Reduce the effects of GH on the body
    • Decrease IGF-1 levels in the bloodstream
  • Radiation therapy to reduce the size of the pituitary adenoma and lower the amount of GH it releases, or secretes

Some people with acromegaly will undergo a combination of the three types of treatments, whereas others will use just one. You and your doctor and/or a multidisciplinary care team will decide together on the treatment approach that meets your unique health needs.

Multidisciplinary care teams are made up of medical, surgical and radiation therapy specialists so that your endocrinologist can easily consult with the other specialists involved in your care.

Check out the true-2-me guest editorial on treatment Considerations for Acromegaly

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